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Retroreflective-type Janus microspheres as a novel contrast agent for enhanced optical coherence tomography
Zhang, Jian1; Liu, Jing2; Wang, Li-Mei3; Li, Zhi-Yuan2; Yuan, Zhen1
2017-06
Source PublicationJOURNAL OF BIOPHOTONICS
ISSN1864-063X
Volume10Issue:6-7Pages:878-886
Abstract

Optical coherence tomography (OCT) is a well-developed technology that utilizes near-infrared light to reconstruct three-dimensional images of biological tissues with micrometer resolution. Improvements of the imaging contrast of the OCT technique are able to further widen its extensive biomedical applications. In this study, Janus microspheres were developed and used as a positive contrast agent for enhanced OCT imaging. Phantom and ex vivo liver tissue experiments as well as in vivo animal tests were conducted, which validated that Janus microspheres, as a novel type of OCT tracer, were very effective in improving the OCT imaging contrast.

KeywordOptical Coherence Tomography Janus Microsphere Retroreflective-type Contrast Enhancement
DOI10.1002/jbio.201600047
URLView the original
Indexed BySCI
Language英语
WOS Research AreaBiochemistry & Molecular Biology ; Biophysics ; Optics
WOS SubjectBiochemical Research Methods ; Biophysics ; Optics
WOS IDWOS:000404558200015
PublisherWILEY-V C H VERLAG GMBH
The Source to ArticleWOS
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Cited Times [WOS]:6   [WOS Record]     [Related Records in WOS]
Document TypeJournal article
CollectionFaculty of Health Sciences
Affiliation1.Bioimaging Core, Faculty of Health Sciences, University of Macau, Taipa, Macau SAR, China.
2.Laboratory of Optical Physics, Institute of Physics, Chinese Academy of Sciences, Beijing, 100190, China.
3.Center for Drug Non-clinical Evaluation and Research, Guangdong Biological Resources Institute, Guangdong Academy of Sciences, Guangzhou, 510900, China.
First Author AffilicationFaculty of Health Sciences
Recommended Citation
GB/T 7714
Zhang, Jian,Liu, Jing,Wang, Li-Mei,et al. Retroreflective-type Janus microspheres as a novel contrast agent for enhanced optical coherence tomography[J]. JOURNAL OF BIOPHOTONICS,2017,10(6-7):878-886.
APA Zhang, Jian,Liu, Jing,Wang, Li-Mei,Li, Zhi-Yuan,&Yuan, Zhen.(2017).Retroreflective-type Janus microspheres as a novel contrast agent for enhanced optical coherence tomography.JOURNAL OF BIOPHOTONICS,10(6-7),878-886.
MLA Zhang, Jian,et al."Retroreflective-type Janus microspheres as a novel contrast agent for enhanced optical coherence tomography".JOURNAL OF BIOPHOTONICS 10.6-7(2017):878-886.
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