UM
Nortriterpenoids from the Fruiting Bodies of the Mushroom Ganoderma resinaceum
Chen, Xian-Qiang; Chen, Ling-Xiao; Zhao, Jing; Tang, Yu-Ping; Li, Shao-Ping
2017-07
Source PublicationMOLECULES
ISSN1420-3049
Volume22Issue:7
AbstractGanoderma resinaceum is usually used as ethnomedicine for immune-regulation, hyperglycemia, and liver disease. To date, only a few chemical constituents have been reported from G. resinaceum. In this study, fifteen nortriterpenoids including six new nortriterpenoids (1-6) and nine known analogs (7-15), were separated and purified from the fruiting bodies of G. resinaceum. New compounds were identified as lucidone I (1), lucidone J (2), lucidone K (3), lucidone I (4), ganosineniol B (5), and ganosineniol C (6), based on analysis of extensive spectroscopic data (high resolution mass spectrometry (HRMS), nuclear magnetic resonance (NMR), infrared (IR), and ultraviolet (UV)). The known compounds were assigned as lucidone A (7), lucidone B (8), lucidone H (9), lucidone E (10), lucidone F (11), lucidone D (12), lucidone C (13), ganoderense F (14), and ganosineniol A (15), by comparing their spectroscopic data with those reported in the literature. Compounds 3, 4, and 7-13 were examined for alpha-glucosidase inhibitory activity and display no significant activity, but the finding may support that the side chain of ganoderma triterpenoids played an important role in alpha-glucosidase inhibitory activity.
KeywordGanoderma resinaceum nortriterpenoid lucidones I-L alpha-glucosidase
DOI10.3390/molecules22071073
URLView the original
Indexed BySCI
Language英语
WOS Research AreaBiochemistry & Molecular Biology ; Chemistry
WOS SubjectBiochemistry & Molecular Biology ; Chemistry, Multidisciplinary
WOS IDWOS:000406621300047
PublisherMDPI AG
The Source to ArticleWOS
Fulltext Access
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Cited Times [WOS]:3   [WOS Record]     [Related Records in WOS]
Document TypeJournal article
CollectionUniversity of Macau
Recommended Citation
GB/T 7714
Chen, Xian-Qiang,Chen, Ling-Xiao,Zhao, Jing,et al. Nortriterpenoids from the Fruiting Bodies of the Mushroom Ganoderma resinaceum[J]. MOLECULES,2017,22(7).
APA Chen, Xian-Qiang,Chen, Ling-Xiao,Zhao, Jing,Tang, Yu-Ping,&Li, Shao-Ping.(2017).Nortriterpenoids from the Fruiting Bodies of the Mushroom Ganoderma resinaceum.MOLECULES,22(7).
MLA Chen, Xian-Qiang,et al."Nortriterpenoids from the Fruiting Bodies of the Mushroom Ganoderma resinaceum".MOLECULES 22.7(2017).
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