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Water solubility is essential for fluorescent probes to image hypochlorous acid in live cells
Xing, Panfei1; Zhang, Zhe1; Niu, Yiming1; Qi, Yaning2; Dong, Lei3; Wang, Chunming1
2018-09-14
Source PublicationCHEMICAL COMMUNICATIONS
ISSN1359-7345
Volume54Issue:71
Abstract

We synthesised four probes and compared their HClO-detecting ability in different solvents. The data showed that only hydrophilic probes could sensitively and accurately detect HClO in live cells. Meanwhile, the addition of organic solvents, as is commonly practised, weakens the oxidising capacity of HClO and thus generates inaccurate outcomes.

DOI10.1039/c8cc04631j
URLView the original
Indexed BySCI
Language英语
WOS Research AreaChemistry
WOS SubjectChemistry, Multidisciplinary
WOS IDWOS:000443170200002
PublisherROYAL SOC CHEMISTRY
The Source to ArticleWOS
Fulltext Access
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Cited Times [WOS]:2   [WOS Record]     [Related Records in WOS]
Document TypeJournal article
CollectionInstitute of Chinese Medical Sciences
Corresponding AuthorDong, Lei; Wang, Chunming
Affiliation1.State Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, Macau SAR
2.Choi Kai Yau College, University of Macau, Macau SAR
3.State Key Laboratory of Pharmaceutical Biotechnology, Nanjing University Institution, Nanjing, China
First Author AffilicationInstitute of Chinese Medical Sciences
Corresponding Author AffilicationInstitute of Chinese Medical Sciences
Recommended Citation
GB/T 7714
Xing, Panfei,Zhang, Zhe,Niu, Yiming,et al. Water solubility is essential for fluorescent probes to image hypochlorous acid in live cells[J]. CHEMICAL COMMUNICATIONS,2018,54(71).
APA Xing, Panfei,Zhang, Zhe,Niu, Yiming,Qi, Yaning,Dong, Lei,&Wang, Chunming.(2018).Water solubility is essential for fluorescent probes to image hypochlorous acid in live cells.CHEMICAL COMMUNICATIONS,54(71).
MLA Xing, Panfei,et al."Water solubility is essential for fluorescent probes to image hypochlorous acid in live cells".CHEMICAL COMMUNICATIONS 54.71(2018).
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