Meloslines A and B, two novel indole alkaloids from Alstonia scholaris

doi:10.1016/j.tetlet.2017.05.094

	Meloslines A and B, two novel indole alkaloids from Alstonia scholaris
	Kuok, Chiu-Fai; Zhang, Jian; Fan, Chun-Lin; Zhang, Qing-Wen; Fan, Run-Zhu; Zhang, Dong-Mei; Zhang, Xiao-Qi; Ye, Wen-Cai
	2017-07-12
Source Publication	TETRAHEDRON LETTERS
ISSN	0040-4039
Volume	58 Issue:28 Pages:2740-2742
Abstract	An unprecedented indole alkaloid melosline A (1), with 6/5/6/6 tetracyclic ring skeleton, together with a new alkaloid melosline B (2) and one known compound (3) were isolated from the leaves and twigs of Alstonia scholaris. The new structures were elucidated by comprehensive spectroscopic analysis. The absolute configuration of compound 1 was confirmed by comparison of experimental data with calculated electronic circular dichroism (ECD). Compound 1 exhibited moderate cytotoxicity against MCF-7 cancer cell lines. (C) 2017 Elsevier Ltd. All rights reserved.
Keyword	Indole alkaloids Alstonia scholaris Absolute configuration Cytotoxicity
DOI	10.1016/j.tetlet.2017.05.094
URL	View the original
Indexed By	SCI ; IC
Language	英语
WOS Research Area	Chemistry
WOS Subject	Chemistry, Organic
WOS ID	WOS:000405048100014
Publisher	PERGAMON-ELSEVIER SCIENCE LTD
The Source to Article	WOS
Fulltext Access	View Full-Text via DOI View Full-Text via Web of Science
Citation statistics	Cited Times [WOS]:1 [WOS Record] [Related Records in WOS]
Document Type	Journal article
Collection	University of Macau
Recommended Citation GB/T 7714	Kuok, Chiu-Fai,Zhang, Jian,Fan, Chun-Lin,et al. Meloslines A and B, two novel indole alkaloids from Alstonia scholaris[J]. TETRAHEDRON LETTERS,2017,58(28):2740-2742.
APA	Kuok, Chiu-Fai.,Zhang, Jian.,Fan, Chun-Lin.,Zhang, Qing-Wen.,Fan, Run-Zhu.,...&Ye, Wen-Cai.(2017).Meloslines A and B, two novel indole alkaloids from Alstonia scholaris.TETRAHEDRON LETTERS,58(28),2740-2742.
MLA	Kuok, Chiu-Fai,et al."Meloslines A and B, two novel indole alkaloids from Alstonia scholaris".TETRAHEDRON LETTERS 58.28(2017):2740-2742.

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