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Therapeutic potential of Rhizoma Alismatis: a review on ethnomedicinal application, phytochemistry, pharmacology, and toxicology
Zhang, Le-Le1; Xu, Wen2; Xu, Yu-Lian1; Chen, Xiuping1; Huang, Mingqing2; Lu, Jin-Jian1
2017-08
Source PublicationANNALS OF THE NEW YORK ACADEMY OF SCIENCES
ISSN0077-8923
Volume1401Issue:1Pages:90-101
Abstract

Rhizoma Alismatis (RA), the dried rhizome of Alisma orientale (Sam.) Juzep, is a common traditional herbal medicine named Ze Xie in Chinese. RA is an important herbal component of a number of well-known Chinese medicinal preparations. It has been used to treat various ailments, such as dysuria, edema, nephropathy, hyperlipidemia, and diabetes. A wide range of chemical compounds, mainly triterpenoids, sesquiterpenoids, and diterpenoids, have been isolated from RA; among which the protostane-type triterpenoids, termed alisols, have attracted the most attention owing to their unique chemical structures and various biological activities. The extract and active compounds of RA possess a wide spectrum of pharmacological effects (e.g., diuretic, antimetabolic disorder, hepatoprotective, immunomodulatory, antiosteoporotic, anti-inflammatory, antitumor, antibacterial, and antiviral activities). Previous toxicological evaluations indicated that the RA extracts are relatively safe and have no serious side effects within certain dose ranges. This paper reviews the up-to-date information on the ethnomedicinal application, phytochemistry, pharmacology, and toxicology of RA. This information will be useful for a better understanding of the therapeutic potential of RA.

KeywordRhizoma Alismatis Ethnomedicinal Application Phytochemistry Pharmacology Toxicology
DOI10.1111/nyas.13381
URLView the original
Indexed BySCI
Language英语
WOS Research AreaScience & Technology - Other Topics
WOS SubjectMultidisciplinary Sciences
WOS IDWOS:000410108700008
PublisherWILEY
The Source to ArticleWOS
Fulltext Access
Citation statistics
Cited Times [WOS]:15   [WOS Record]     [Related Records in WOS]
Document TypeJournal article
CollectionInstitute of Chinese Medical Sciences
Affiliation1.State Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau,Macao, China
2.College of Pharmacy, Fujian University of Traditional Chinese Medicine, Fuzhou, China
First Author AffilicationInstitute of Chinese Medical Sciences
Recommended Citation
GB/T 7714
Zhang, Le-Le,Xu, Wen,Xu, Yu-Lian,et al. Therapeutic potential of Rhizoma Alismatis: a review on ethnomedicinal application, phytochemistry, pharmacology, and toxicology[J]. ANNALS OF THE NEW YORK ACADEMY OF SCIENCES,2017,1401(1):90-101.
APA Zhang, Le-Le,Xu, Wen,Xu, Yu-Lian,Chen, Xiuping,Huang, Mingqing,&Lu, Jin-Jian.(2017).Therapeutic potential of Rhizoma Alismatis: a review on ethnomedicinal application, phytochemistry, pharmacology, and toxicology.ANNALS OF THE NEW YORK ACADEMY OF SCIENCES,1401(1),90-101.
MLA Zhang, Le-Le,et al."Therapeutic potential of Rhizoma Alismatis: a review on ethnomedicinal application, phytochemistry, pharmacology, and toxicology".ANNALS OF THE NEW YORK ACADEMY OF SCIENCES 1401.1(2017):90-101.
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