UM  > 中華醫藥研究院
Biological and clinical implications of herbal medicine and natural products for the treatment of inflammatory bowel disease
Guo, Bao-Jian1; Bian, Zhao-Xiang2; Qiu, Hong-Cong3; Wang, Yi-Tao1; Wang, Ying1
2017-08
Source PublicationANNALS OF THE NEW YORK ACADEMY OF SCIENCES
ISSN0077-8923
Volume1401Issue:1Pages:37-48
Abstract

Inflammatory bowel disease (IBD) is a group of chronic inflammatory disorders that includes Crohn's disease (CD) and ulcerative colitis (UC). Homeostasis of various regulatory factors involved with intestinal immunity is disrupted in IBD, including the intestinal epithelial barrier, macrophages, and cellular mediators such as cytokines and chemokines. No successful treatment is currently available for the management of IBD. Natural products and herbal medicines have exhibited efficacy for UC and CD in experimental models and clinical trials with the following activities: (1) maintenance of integrity of the intestinal epithelial barrier, (2) regulation of macrophage activation, (3) modulation of innate and adaptive immune response, and (4) inhibition of TNF- activity. Here, we discuss the major factors involved in the pathogenesis of IBD and the current development of natural products and herbs for the treatment of IBD.

KeywordInflammatory Bowel Disease Crohn's Disease Ulcerative Colitis Herbal Medicine Natural Products
DOIhttp://doi.org/10.1111/nyas.13414
URLView the original
Indexed BySCI
Language英语
WOS Research AreaScience & Technology - Other Topics
WOS SubjectMultidisciplinary Sciences
WOS IDWOS:000410108700004
PublisherWILEY
The Source to ArticleWOS
Fulltext Access
Citation statistics
Cited Times [WOS]:10   [WOS Record]     [Related Records in WOS]
Document TypeJournal article
CollectionInstitute of Chinese Medical Sciences
Corresponding AuthorWang, Yi-Tao; Wang, Ying
Affiliation1.State Key Laboratory of Quality Research in Chinese Medicine and Institute of Chinese Medical Sciences, University ofMacau, Taipa, Macao SAR, China
2.School of Chinese Medicine and Hong Kong Chinese Medicine Study Centre, Hong KongBaptist University, Kowloon Tong, Hong Kong, China
3.Guangxi Institute of Traditional Medical and Pharmaceutical Sciencesand Guangxi Key Laboratory of Traditional Chinese Medicine Quality Standards, Nanning, China
First Author AffilicationInstitute of Chinese Medical Sciences
Corresponding Author AffilicationInstitute of Chinese Medical Sciences
Recommended Citation
GB/T 7714
Guo, Bao-Jian,Bian, Zhao-Xiang,Qiu, Hong-Cong,et al. Biological and clinical implications of herbal medicine and natural products for the treatment of inflammatory bowel disease[J]. ANNALS OF THE NEW YORK ACADEMY OF SCIENCES,2017,1401(1):37-48.
APA Guo, Bao-Jian,Bian, Zhao-Xiang,Qiu, Hong-Cong,Wang, Yi-Tao,&Wang, Ying.(2017).Biological and clinical implications of herbal medicine and natural products for the treatment of inflammatory bowel disease.ANNALS OF THE NEW YORK ACADEMY OF SCIENCES,1401(1),37-48.
MLA Guo, Bao-Jian,et al."Biological and clinical implications of herbal medicine and natural products for the treatment of inflammatory bowel disease".ANNALS OF THE NEW YORK ACADEMY OF SCIENCES 1401.1(2017):37-48.
Related Services
Recommend this item
Bookmark
Usage statistics
Export to Endnote
Google Scholar
Similar articles in Google Scholar
[Guo, Bao-Jian]'s Articles
[Bian, Zhao-Xiang]'s Articles
[Qiu, Hong-Cong]'s Articles
Baidu academic
Similar articles in Baidu academic
[Guo, Bao-Jian]'s Articles
[Bian, Zhao-Xiang]'s Articles
[Qiu, Hong-Cong]'s Articles
Bing Scholar
Similar articles in Bing Scholar
[Guo, Bao-Jian]'s Articles
[Bian, Zhao-Xiang]'s Articles
[Qiu, Hong-Cong]'s Articles
Terms of Use
No data!
Social Bookmark/Share
All comments (0)
No comment.
 

Items in the repository are protected by copyright, with all rights reserved, unless otherwise indicated.