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A comprehensive review of agrimoniin
Grochowski, Daniel M.1; Skalicka-Wozniak, Krystyna2; Orhan, Ilkay Erdogan3; Xiao, Jianbo4,5; Locatelli, Marcello6; Piwowarski, Jakub P.7; Granica, Sebastian7; Tomczyk, Michal1

Plant tannins are a unique class of polyphenols with relatively high molecular weights. Within the ellagitannins group, agrimoniin--dimeric ellagitannin--is one of the most representative compounds found in many plant materials belonging to the Rosaceae family. Agrimoniin was first isolated in 1982 from roots of Agrimonia pilosa Ledeb. (Rosaceae), a plant traditionally used in Japan and China as an antidiarrheal, hemostatic, and antiparasitic agent. Agrimoniin is a constituent of medicinal plants, which are often applied orally in the form of infusions, decoctions, or tinctures. It is also present in commonly consumed food products, such as strawberries and raspberries. It is metabolized by human gut microbiota into a series of low-molecular-weight urolithins with proven anti-inflammatory and anticancer in vivo and in vitro bioactivities. The compound has received widespread interest owing to some interesting biological effects and therapeutic activities, which we elaborate in the present review. Additionally, we present an overview of the techniques used for the analysis, isolation, and separation of agrimoniin from the practical perspective.

KeywordAgrimoniin Ellagitannin Chemistry Metabolism Hyphated Techniques Biological Activity
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Indexed BySCI
WOS Research AreaScience & Technology - Other Topics
WOS SubjectMultidisciplinary Sciences
WOS IDWOS:000410108700013
The Source to ArticleWOS
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Cited Times [WOS]:5   [WOS Record]     [Related Records in WOS]
Document TypeJournal article
CollectionInstitute of Chinese Medical Sciences
Affiliation1.Department of Pharmacognosy, Faculty of Pharmacy with the Division of Laboratory Medicine, Medical University ofBiałystok, Białystok, Poland
2.Department of Pharmacognosy with Medicinal Plant Unit, Faculty of Pharmacy, MedicalUniversity of Lublin, Lublin, Poland
3.Department of Pharmacognosy, Faculty of Pharmacy, Gazi University, Ankara, Turkey
4.Institute of Chinese Medical Sciences, University of Macau, Taipa, Macau
5.College of Food Science, Fujian Agriculture andForestry University, Fuzhou, China
6.Department of Pharmacy, University “G. d’Annunzio” of Chieti-Pescara, Chieti, Italy
7.Department of Pharmacognosy and Molecular Basis of Phytotherapy, Faculty of Pharmacy, Medical University of Warsaw,Warsaw, Poland
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Grochowski, Daniel M.,Skalicka-Wozniak, Krystyna,Orhan, Ilkay Erdogan,et al. A comprehensive review of agrimoniin[J]. ANNALS OF THE NEW YORK ACADEMY OF SCIENCES,2017,1401(1):166-180.
APA Grochowski, Daniel M..,Skalicka-Wozniak, Krystyna.,Orhan, Ilkay Erdogan.,Xiao, Jianbo.,Locatelli, Marcello.,...&Tomczyk, Michal.(2017).A comprehensive review of agrimoniin.ANNALS OF THE NEW YORK ACADEMY OF SCIENCES,1401(1),166-180.
MLA Grochowski, Daniel M.,et al."A comprehensive review of agrimoniin".ANNALS OF THE NEW YORK ACADEMY OF SCIENCES 1401.1(2017):166-180.
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