UM
The Development of G-Quadruplex-Based Assays for the Detection of Small Molecules and Toxic Substances
Ma, Dik-Lung; Wu, Chun; Dong, Zhen-Zhen; Tam, Wing-Sze; Wong, Sze-Wan; Yang, Chao; Li, Guodong; Leung, Chung-Hang
2017-08-04
Source PublicationCHEMISTRY-AN ASIAN JOURNAL
ISSN1861-4728
Volume12Issue:15Pages:1851-1860
AbstractG-Quadruplexes can be induced to form guaninerich DNA sequences by certain small molecules or metal ions. In concert with an appropriate signal transducer, such as a fluorescent dye or a phosphorescent metal complex, the ligand-recognition event can be transduced into a luminescent response. This focus review aims to highlight recent examples of aptamer-based and metal-mediated G-quadruplex assays for the detection of small molecules and toxic substances in the last three years. We discuss the mechanisms and features of the different assays and present an outlook and a perspective for the future of this field.
Keywordaptamers assays G-quadruplexes luminescence transition metals
DOI10.1002/asia.201700533
URLView the original
Indexed BySCI
Language英语
WOS Research AreaChemistry
WOS SubjectChemistry, Multidisciplinary
WOS IDWOS:000409251800002
PublisherWILEY-V C H VERLAG GMBH
The Source to ArticleWOS
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Citation statistics
Cited Times [WOS]:5   [WOS Record]     [Related Records in WOS]
Document TypeJournal article
CollectionUniversity of Macau
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GB/T 7714
Ma, Dik-Lung,Wu, Chun,Dong, Zhen-Zhen,et al. The Development of G-Quadruplex-Based Assays for the Detection of Small Molecules and Toxic Substances[J]. CHEMISTRY-AN ASIAN JOURNAL,2017,12(15):1851-1860.
APA Ma, Dik-Lung.,Wu, Chun.,Dong, Zhen-Zhen.,Tam, Wing-Sze.,Wong, Sze-Wan.,...&Leung, Chung-Hang.(2017).The Development of G-Quadruplex-Based Assays for the Detection of Small Molecules and Toxic Substances.CHEMISTRY-AN ASIAN JOURNAL,12(15),1851-1860.
MLA Ma, Dik-Lung,et al."The Development of G-Quadruplex-Based Assays for the Detection of Small Molecules and Toxic Substances".CHEMISTRY-AN ASIAN JOURNAL 12.15(2017):1851-1860.
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