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Time-Regulated Actuation Signal for Enhancement of Droplet Transportation in Digital Microfluidics,
Tianlan Chen; Cheng Dong; Jie Gao; Yanwei Jia; Pui-In Mak; Mang-I Vai; Rui P. Martins
2014
Conference NameLAB-ON-A-CHIP ASIA Microfluidics & Point-of-Care Diagnostics
Source PublicationSELECTBIO Lab-on-a-Chip Asia 2014, Microfluidics and Point-of-Care Diagnostics
Conference DateNovember 2014
Conference PlaceSingapore
Abstract

Digital Microfluidics (DMF) is an attractive technology for biological/chemical micro-reactions due to its distinct droplet manageability via electronic automation. However, the limited velocity of droplet transportation has hindered DMF from being utilized in high throughput applications. Here we introduce two novel control-engaged electrode-driving techniques: Natural Discharge after Pulse (NDAP) and Cooperative Electrodes (CE). NDAP is based on a series of DC pulses and multi-cycle natural discharging coordinated with the droplet dynamic motions, facilitating real-time droplet position sensing. CE is an early-charging of the target electrode before discharging the current one to avoid droplet deformation and local vibration at the gaps between two electrodes. By combining NDAP with CE, we have for the first time increased the droplet transportation efficiency without compromising the lifetime of electrodes in DMF. This work, together with our previous publications, should be valuable for scientists and engineers working on enhancing the throughput and the reliability of control-engaged DMF systems for automated applications.

URLView the original
Fulltext Access
Document TypeConference paper
CollectionDEPARTMENT OF ELECTRICAL AND COMPUTER ENGINEERING
AffiliationState Key Laboratory of Analog and Mixed-Signal VLSI and FST-ECE, University of Macau, Macao, China
First Author AffilicationUniversity of Macau
Recommended Citation
GB/T 7714
Tianlan Chen,Cheng Dong,Jie Gao,et al. Time-Regulated Actuation Signal for Enhancement of Droplet Transportation in Digital Microfluidics,[C],2014.
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