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Modular nuclear magnetic resonance-digital microfluidic system for biological assays
Ka-Meng LEI; Pui-ln MAK; Man-Kay LAW; Rui Paulo Da Silva Martins
Rights HolderUniversity of Macau
Date Available2017-04-13
CountryUnited States
Subtype发明专利
Abstract

A portable modular NMR-DMF system for performing chemical/biological assays. The systemcomprises a PCB having an NMR electronic circuit thereon, wherein the NMR electronic circuit includes a figure-8 shaped RF coil generating a plane-parallel magnetic field. A planar DMF chip comprises a platform comprising an array of electrodes, the array of electrodes including a sensing site located under the figure-8 shaped RF coil. A portable magnet is disposed parallel to the DMF chip and the RF coil. The array of electrodes is configured to receive a sample under detection, move the sample along the array, mix the sample with a probe in the form of at least one droplet with target-specific nanoparticles, and move the mixed sample to the sensing site. A magnetic field corresponding to the mixed sample under detection is produced at the sensing site. The figure-8 shaped RF coil acts to transduce the magnetic field produced at the sensing site to a voltage signal. The NMR electronic circuit receives and processes the voltage signal to produce a resultant signal for analysis.

Application Date2015-10-13
Patent NumberUS20170102345A1
Language英语
Application NumberUS14881615
Open (Notice) NumberUS20170102345A1
Fulltext Access
Document TypePatent
CollectionFaculty of Science and Technology
INSTITUTE OF MICROELECTRONICS
DEPARTMENT OF ELECTRICAL AND COMPUTER ENGINEERING
AffiliationUniversity of Macau
Recommended Citation
GB/T 7714
Ka-Meng LEI,Pui-ln MAK,Man-Kay LAW,et al. Modular nuclear magnetic resonance-digital microfluidic system for biological assays. US20170102345A1.
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