UM  > 科技學院  > 電機及電腦工程系
CMOS biosensors for in vitro diagnosis–transducing mechanisms and applications
Ka-Meng Lei1,2; Pui-In Mak1,2; Man-Kay Law1; Rui P. Martins1,2,3
2016-09-09
Source PublicationLab on a Chip
ISSN1473-0197
Volume16Issue:19Pages:3664-3681
Abstract

Complementary metal oxide semiconductor (CMOS) technology enables low-cost and large-scale integration of transistors and physical sensing materials on tiny chips (e.g., <1 cm2), seamlessly combining the two key functions of biosensors: transducing and signal processing. Recent CMOS biosensors unified different transducing mechanisms (impedance, fluorescence, and nuclear spin) and readout electronics have demonstrated competitive sensitivity for in vitro diagnosis, such as detection of DNA (down to 10 aM), protein (down to 10 fM), or bacteria/cells (single cell). Herein, we detail the recent advances in CMOS biosensors, centering on their key principles, requisites, and applications. Together, these may contribute to the advancement of our healthcare system, which should be decentralized by broadly utilizing point-of-care diagnostic tools.

DOIhttp://dx.doi.org/10.1039/C6LC01002D
Indexed BySCI
Language英语
WOS Research AreaBiochemistry & Molecular Biology ; Chemistry ; Science & Technology - Other Topics
WOS SubjectBiochemical Research Methods ; Chemistry, Multidisciplinary ; Chemistry, Analytical ; Nanoscience & Nanotechnology
WOS IDWOS:000384467100004
全文获取链接
引用统计
被引频次[WOS]:10   [WOS记录]     [WOS相关记录]
Document TypeJournal article
专题DEPARTMENT OF ELECTRICAL AND COMPUTER ENGINEERING
INSTITUTE OF MICROELECTRONICS
Corresponding AuthorPui-In Mak
Affiliation1.State-Key Laboratory of Analog and Mixed-Signal VLSI, University of Macau, China
2.On leave from Instituto Superior Técnico, Universidade de Lisboa, Portugal
3.Faculty of Science and Technology, Dept. of ECE, University of Macau, China
First Author AffilicationUniversity of Macau
Corresponding Author AffilicationUniversity of Macau
推荐引用方式
GB/T 7714
Ka-Meng Lei,Pui-In Mak,Man-Kay Law,et al. CMOS biosensors for in vitro diagnosis–transducing mechanisms and applications[J]. Lab on a Chip,2016,16(19):3664-3681.
APA Ka-Meng Lei,Pui-In Mak,Man-Kay Law,&Rui P. Martins.(2016).CMOS biosensors for in vitro diagnosis–transducing mechanisms and applications.Lab on a Chip,16(19),3664-3681.
MLA Ka-Meng Lei,et al."CMOS biosensors for in vitro diagnosis–transducing mechanisms and applications".Lab on a Chip 16.19(2016):3664-3681.
个性服务
推荐该条目
保存到收藏夹
查看访问统计
导出为Endnote文件
Google Scholar
中相似的文章 Google Scholar
[Ka-Meng Lei]的文章
[Pui-In Mak]的文章
[Man-Kay Law]的文章
Baidu academic
中相似的文章 Baidu academic
[Ka-Meng Lei]的文章
[Pui-In Mak]的文章
[Man-Kay Law]的文章
Bing Scholar
中相似的文章 Bing Scholar
[Ka-Meng Lei]的文章
[Pui-In Mak]的文章
[Man-Kay Law]的文章
相关权益政策
暂无数据
收藏/分享
所有评论 (0)
暂无评论
 

除非特别说明,本系统中所有内容都受版权保护,并保留所有权利。