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Strategies to reduce radiation dose in cardiac PET/CT
Tung Hsin Wu1; Nien-Yun Wu1; Shyh-Jen Wang1,2; Jay Wu3; Greta S.P. Mok4; Ching-Ching Yang5; Tzung-Chi Huang6
2011-08-21
Source PublicationNuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment
ISSN0168-9002
Volume648Issue:1Pages:Pages S158-S162
Abstract

Background: Our aim was to investigate CT dose reduction strategies on a hybrid PET/CT scanner for cardiac applications. Materials: Image quality and dose estimation of different CT scanning protocols for CT coronary angiography (CTCA), and CT-based attenuation correction for PET imaging were investigated. Fifteen patients underwent CTCA, perfusion PET imaging at rest and under stress, and FDG PET for myocardial viability. These patients were divided into three groups based on the CTCA technique performed: retrospectively gated helical (RGH), ECG tube current modulation (ETCM), and prospective gated axial (PGA) acquisitions. All emission images were corrected for photon attenuation using CT images obtained by default setting and an ultra-low dose CT (ULDCT) scan. Results: Radiation dose in RGH technique was 22.274.0 mSv. It was reduced to 10.9570.82 and 4.1370.31 mSv using ETCM and PGA techniques, respectively. Radiation dose in CT transmission scan was reduced by 96.5% (from 4.5370.5 to 0.1670.01 mSv) when applying ULDCT as compared to the default CT. No significant difference in terms of image quality was found among various protocols. Conclusion: The proposed CT scanning strategies, i.e. ETCM or PGA for CTCA and ULDCT for PET attenuation correction, could reduce radiation dose up to 47% without degrading imaging quality in an integrated cardiac PET/CT coronary artery examination.

KeywordCt Coronary Angiography Ct-based Attenuation Correction Radiation Dose
DOIhttps://doi.org/10.1016/j.nima.2010.12.052
Indexed BySCI
Language中文
WOS Research AreaInstruments & Instrumentation ; Nuclear Science & Technology ; Physics
WOS SubjectInstruments & Instrumentation ; Nuclear Science & Technology ; Physics, Nuclear ; Physics, Particles & Fields
WOS IDWOS:000305376900042
PublisherELSEVIER SCIENCE BV, PO BOX 211, 1000 AE AMSTERDAM, NETHERLANDS
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Cited Times [WOS]:1   [WOS Record]     [Related Records in WOS]
Document TypeJournal article
CollectionDEPARTMENT OF ELECTRICAL AND COMPUTER ENGINEERING
Corresponding AuthorChing-Ching Yang; Tzung-Chi Huang
Affiliation1.Department of Biomedical Imaging and Radiological Sciences, National Yang-Ming University, Taipei, Taiwan
2.Department of Nuclear Medicine, Taipei Veterans General Hospital, Taipei, Taiwan
3.Institute of Radiological science, Central Taiwan University of Science and Technology, Taichung, Taiwan
4.Department of Electrical and Electronics Engineering, Faculty of Science and Technology, University of Macau, Macau
5.Department of Radiological Technology, Tzu Chi College of Technology, 880, Sec.2, Chien-kuo Rd. Hualien 970, Taiwan
6.Department of Biomedical Imaging and Radiological Science, China Medical University, No.91 Hsueh-Shih Road,Taichung 40402, Taiwan
Recommended Citation
GB/T 7714
Tung Hsin Wu,Nien-Yun Wu,Shyh-Jen Wang,et al. Strategies to reduce radiation dose in cardiac PET/CT[J]. Nuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment,2011,648(1):Pages S158-S162.
APA Tung Hsin Wu.,Nien-Yun Wu.,Shyh-Jen Wang.,Jay Wu.,Greta S.P. Mok.,...&Tzung-Chi Huang.(2011).Strategies to reduce radiation dose in cardiac PET/CT.Nuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment,648(1),Pages S158-S162.
MLA Tung Hsin Wu,et al."Strategies to reduce radiation dose in cardiac PET/CT".Nuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment 648.1(2011):Pages S158-S162.
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