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Evaluation of Respiratory Gating Schemes for Cardiac SPECT Using a Population of Phantoms
Duo Zhang1; Michael Ghaly2; Qi Zhang1; Greta S. P. Mok1
2018-11-12
Conference NameIEEE Nuclear Science Symposium and Medical Imaging Conference (NSS/MIC) / 24th International Symposium on Room-Temperature
Source Publication2017 IEEE Nuclear Science Symposium and Medical Imaging Conference, NSS/MIC 2017 - Conference Proceedings
Conference DateOCT 21-28, 2017
Conference PlaceAtlanta, GA
Abstract

Respiratory gating was proposed to reduce motion blur in cardiac SPECT. This study aims to evaluate 3 respiratory gating methods for cardiac SPECT. We used a population of 4D XCAT phantoms to simulate 10 patients injected with Tc-99mMIBI, 6 with normal heart and 4 with heart defects. Phantoms varied in gender, body size, heart size, activity distribution and breathing pattern. For each phantom, 3 respiratory cycles were divided into 288 frames which were grouped to 6 gates with: (1) equal amplitude gating (AG); (2) amplitude gating with equal counts (CG) and (3) equal time gating (TG). Average activity and attenuation maps in each gate represented gated SPECT and CT. The end-expiratory and end-inspiratory phases were used as references. One hundred and twenty noise-free projections were generated from RAO to LPO using an analytical LEHR projector and reconstructed by OS-EM with 200 updates, using gated CT for attenuation correction. Reconstructed images in each gate were registered to referenced images using affine+bspline method, then averaged and reoriented to generate shortaxis images and polar plots. Relative difference (RD) of the average image intensity was computed at each segment in 17segment analysis based on the references. For all phantoms, the maximum {\mathrm {RD}}-{\mathrm {ALL}} of AG, CG and TG were 7.41 ± 4.45%, 7.10 ± 3.58% and 12.33 ± 3.80% when registered to end-expiration and 6.38 ± 2.68%, 7.22 ± 3.97% and 13.73 ± 4.95% when registered to end-inspiration. We conclude that the amplitude based methods (AG and CG) shows better performance in motion reduction.

DOIhttp://doi.org/10.1109/NSSMIC.2017.8532850
URLView the original
Indexed BySCI
Language英语
WOS Research AreaEngineering ; Nuclear Science & Technology ; Radiology, Nuclear Medicine & Medical Imaging
WOS SubjectEngineering, Electrical & Electronic ; Nuclear Science & Technology ; Radiology, Nuclear Medicine & Medical Imaging
WOS IDWOS:000455836200259
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Document TypeConference paper
CollectionDEPARTMENT OF ELECTRICAL AND COMPUTER ENGINEERING
Affiliation1.Department of Electrical and Computer Engineering, Faculty of Science and Technology, University of Macau, Macau SAR, People’s Republic of China
2.Department of Radiology and Radiological Science, Johns Hopkins University, Baltimore, MD, USA
First Author AffilicationFaculty of Science and Technology
Recommended Citation
GB/T 7714
Duo Zhang,Michael Ghaly,Qi Zhang,et al. Evaluation of Respiratory Gating Schemes for Cardiac SPECT Using a Population of Phantoms[C],2018.
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