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Design and evaluation of two multi-pinhole collimators for brain SPECT
Chen, Ling1; Tsui, Benjamin M. W.3; Mok, Greta S. P.1,2
2017-10
Source PublicationANNALS OF NUCLEAR MEDICINE
ISSN0914-7187
Volume31Issue:8Pages:636-648
Abstract

Objective SPECT is a powerful tool for diagnosing or staging brain diseases such as Alzheimer's disease (AD) and Parkinson's disease (PD) but is limited by its inferior resolution and sensitivity. At the same time, pinhole SPECT provides superior resolution and detection efficiency trade-off as compared to the conventional parallel-hole collimator for imaging small field-of-view (FOV), which fits for the case of brain imaging. In this study, we propose to develop and evaluate two multi-pinhole (MPH) collimator designs to improve the imaging of cerebral blood flow and striatum.

KeywordBrain Spect Multi-pinhole Alzheimer's Disease (Ad) Parkinson's Disease (Pd)
DOIhttp://doi.org/10.1007/s12149-017-1195-y
URLView the original
Indexed BySCI
Language英语
WOS Research AreaRadiology, Nuclear Medicine & Medical Imaging
WOS SubjectRadiology, Nuclear Medicine & Medical Imaging
WOS IDWOS:000411969000010
PublisherSPRINGER
The Source to ArticleWOS
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被引频次[WOS]:4   [WOS记录]     [WOS相关记录]
Document TypeJournal article
专题Faculty of Health Sciences
Corresponding AuthorMok, Greta S. P.
Affiliation1.Biomedical Imaging Laboratory (BIG), Department of Electrical and Computer Engineering, Faculty of Science and Technology, University of Macau, Avenida da Universidade, Taipa, Macau SAR, China
2.Faculty of Health Sciences, University of Macau, Avenida da Universidade, Taipa, Macau SAR, China
3.Division of Medical Imaging Physics, The Russell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins University, Baltimore, MD 21287, USA
First Author AffilicationFaculty of Science and Technology
Corresponding Author AffilicationFaculty of Science and Technology;  Faculty of Health Sciences
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Chen, Ling,Tsui, Benjamin M. W.,Mok, Greta S. P.. Design and evaluation of two multi-pinhole collimators for brain SPECT[J]. ANNALS OF NUCLEAR MEDICINE,2017,31(8):636-648.
APA Chen, Ling,Tsui, Benjamin M. W.,&Mok, Greta S. P..(2017).Design and evaluation of two multi-pinhole collimators for brain SPECT.ANNALS OF NUCLEAR MEDICINE,31(8),636-648.
MLA Chen, Ling,et al."Design and evaluation of two multi-pinhole collimators for brain SPECT".ANNALS OF NUCLEAR MEDICINE 31.8(2017):636-648.
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