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Quality of life in Chinese patients with schizophrenia: A meta-analysis
Lu, Li1; Zeng, Liang-Nan2; Zong, Qian-Qian3; Rao, Wen-Wang1; Ng, Chee H.4; Ungvari, Gabor S.5; Li, Jun6; An, Feng-Rong7; Xiang, Yu-Tao8
2018-10
Source PublicationPSYCHIATRY RESEARCH
ISSN0165-1781
Volume268Pages:392-399
Abstract

The impact of schizophrenia on quality of life (QOL) is significantly influenced by sociocultural factors. This meta-analysis systematically compared QOL between patients with schizophrenia and healthy controls in China. PubMed, PsycINFO, Embase, Chinese National Knowledge Infrastructure (CNKI), SinoMed and WanFang data-bases were searched to identify case-control studies. Standardized mean differences (SMDs) and 95% confidence interval (CI) were calculated using random effect models. Eighteen case-control studies comparing QOL between schizophrenia patients (n = 2,425) and healthy controls (n = 2,072) were included in the analyses. Compared with healthy controls, schizophrenia patients had significantly poorer overall QOL [11 studies; SMD:-1.07 (95%CI:-1.44, -0.70), P < 0.001] as well as in the physical, psychological, social and environmental QOL domains. Subgroup analyses revealed that poorer QOL was significantly associated with diagnostic criteria, study location, female gender, older age and inpatient status. Older schizophrenia patients had lower physical and psychological QOL, while inpatients had lower psychological QOL. In conclusion, compared with healthy controls, schizophrenia patients in China have significantly lower QOL.

KeywordSchizophrenia Quality Of Life Meta-analysis China
DOIhttp://doi.org/10.1016/j.psychres.2018.07.003
URLView the original
Indexed BySCI ; SSCI ; SSCI
Language英语
WOS Research AreaPsychiatry
WOS SubjectPsychiatry
WOS IDWOS:000445990300063
PublisherELSEVIER IRELAND LTD
The Source to ArticleWOS
Fulltext Access
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Cited Times [WOS]:3   [WOS Record]     [Related Records in WOS]
Document TypeJournal article
CollectionFaculty of Health Sciences
Corresponding AuthorAn, Feng-Rong; Xiang, Yu-Tao
Affiliation1.Unit of Psychiatry, Faculty of Health Sciences, University of Macau, Macao, SAR, China.
2.The Affiliated Hospital of Southwest Medical University, Luzhou, China.
3.School of Nursing, Capital Medical University, Beijing, China; The National Clinical Research Center for Mental Disorders, China &Center of Depression, Beijing Institute for Brain Disorders & Mood Disorders Center, Beijing Anding Hospital, Capital Medical University, Beijing, China
4.Department of Psychiatry, University of Melbourne, Melbourne, Australia.
5.University of Notre Dame Australia & Graylands Hospital, Perth, Australia.
6.State Key Laboratory of Cognitive Neuroscience and Learning & IDG/McGovern Institute for Brain Research, Beijing Normal University, China.
7.The National Clinical Research Center for Mental Disorders, China &Center of Depression, Beijing Institute for Brain Disorders & Mood Disorders Center, Beijing Anding Hospital, Capital Medical University, Beijing, China
8.Unit of Psychiatry, Faculty of Health Sciences, University of Macau, Macao, SAR, China.
First Author AffilicationFaculty of Health Sciences
Corresponding Author AffilicationFaculty of Health Sciences
Recommended Citation
GB/T 7714
Lu, Li,Zeng, Liang-Nan,Zong, Qian-Qian,et al. Quality of life in Chinese patients with schizophrenia: A meta-analysis[J]. PSYCHIATRY RESEARCH,2018,268:392-399.
APA Lu, Li.,Zeng, Liang-Nan.,Zong, Qian-Qian.,Rao, Wen-Wang.,Ng, Chee H..,...&Xiang, Yu-Tao.(2018).Quality of life in Chinese patients with schizophrenia: A meta-analysis.PSYCHIATRY RESEARCH,268,392-399.
MLA Lu, Li,et al."Quality of life in Chinese patients with schizophrenia: A meta-analysis".PSYCHIATRY RESEARCH 268(2018):392-399.
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