UM
A new flexible manufacturing process for tailoring release rates in controlled release packaging and drug delivery systems
Jin X.2; Zumbrunnen D.A.2; Balasubramanian A.1; Yam K.1
2009-11-25
Source PublicationAnnual Technical Conference - ANTEC, Conference Proceedings
Volume5
Pages2521-2525
AbstractSmart blenders controllably form multi-component polymer melts into a wide variety of fine-scale structural arrangements. The machines operate on the principal of chaotic advection, a recent subfield of fluid mechanics. Because structure of a composite material influences greatly additive diffusion and matrix dissolution, this processing method may be useful for designing medications, transdermal patches, implants, and sutures in medical applications. It may also provide desired release rates of active compounds such as antioxidants and antimicrobial from packaging films to enhance the quality and safety of food. In this paper, an ability to alter release rates of tocopherol, a natural antioxidant, is demonstrated via on-line specification of a process parameter governing blend morphology in extruded films.
KeywordActive packaging Chaotic advection Chaotic mixing Controlled release Drug delivery Smart blending
URLView the original
Language英語
Fulltext Access
Document TypeConference paper
CollectionUniversity of Macau
Affiliation1.Rutgers, The State University of New Jersey
2.Clemson University
Recommended Citation
GB/T 7714
Jin X.,Zumbrunnen D.A.,Balasubramanian A.,et al. A new flexible manufacturing process for tailoring release rates in controlled release packaging and drug delivery systems[C],2009:2521-2525.
Related Services
Recommend this item
Bookmark
Usage statistics
Export to Endnote
Google Scholar
Similar articles in Google Scholar
[Jin X.]'s Articles
[Zumbrunnen D.A.]'s Articles
[Balasubramanian A.]'s Articles
Baidu academic
Similar articles in Baidu academic
[Jin X.]'s Articles
[Zumbrunnen D.A.]'s Articles
[Balasubramanian A.]'s Articles
Bing Scholar
Similar articles in Bing Scholar
[Jin X.]'s Articles
[Zumbrunnen D.A.]'s Articles
[Balasubramanian A.]'s Articles
Terms of Use
No data!
Social Bookmark/Share
All comments (0)
No comment.
 

Items in the repository are protected by copyright, with all rights reserved, unless otherwise indicated.