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Study on antibacterial performance and biocompatibility of a novel phosphorus-magnesium fiber
Wu, Wei; Chen, Jia; Sun, Da; Kong, Xiangjun; Xu, Dake; Wang, Yi; Luo, Li; Zhang, Kun; Xiao, Keshen; Wang, Guixue
2017-12-15
Source PublicationMATERIALS LETTERS
ISSN0167-577X
Volume209Pages:562-565
AbstractThe present study was intended to investigate the antibacterial performance and biocompatibility of a novel phosphorus-magnesium fiber (PMF). The PMF was found to exhibit excellent antibacterial performance against methicillin-resistant Staphylococcus aureus and Candida albicans, exceeding 95% when the PMF concentration was higher than 500 mu g mL (-1). MTS analysis was performed to assess the in vitro cytotoxicity of PMF, which showed PMF with a concentration range of 100-1000 mg L (-1) had no significant toxic effects on L929 fibroblast cells. In addition, the in vivo toxicity assay of PMF was studied in zebrafish (Danio rerio) embryos, and the results confirmed little toxicity at effective antibacterial concentration. Hence, PMF was proved to be a potential coating or filling material with promising antibacterial performance for in implantable medical devices. (c) 2017 Elsevier B.V. All rights reserved.
KeywordBiomaterials Nanoparticles Phosphorous-magnesium fiber Antibacterial performance Zebrafish
DOI10.1016/j.matlet.2017.08.099
URLView the original
Indexed BySCI
Language英语
WOS Research AreaMaterials Science ; Physics
WOS SubjectMaterials Science, Multidisciplinary ; Physics, Applied
WOS IDWOS:000413124300143
PublisherELSEVIER SCIENCE BV
The Source to ArticleWOS
Fulltext Access
Citation statistics
Document TypeJournal article
CollectionUniversity of Macau
Recommended Citation
GB/T 7714
Wu, Wei,Chen, Jia,Sun, Da,et al. Study on antibacterial performance and biocompatibility of a novel phosphorus-magnesium fiber[J]. MATERIALS LETTERS,2017,209:562-565.
APA Wu, Wei.,Chen, Jia.,Sun, Da.,Kong, Xiangjun.,Xu, Dake.,...&Wang, Guixue.(2017).Study on antibacterial performance and biocompatibility of a novel phosphorus-magnesium fiber.MATERIALS LETTERS,209,562-565.
MLA Wu, Wei,et al."Study on antibacterial performance and biocompatibility of a novel phosphorus-magnesium fiber".MATERIALS LETTERS 209(2017):562-565.
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