UM  > 科技學院  > 電機及電腦工程系
Digital microfluidic chip with blade structures for precise droplet splitting
C. Dong1,2; Y.W. Jia1; T.L. Chen1,2; J. Gao1; L. Wan1; P.I. Mak1,2; M.I. Vai1,2; R. P.Martins1,2,3
2016
Conference Name20th International Conference on Miniaturized Systems for Chemistry and Life Sciences
Source Publication20th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2016
Pages892-893
Conference Date9-13 October, 2016
Conference PlaceDublin, Ireland
CountryIreland
Abstract

We present here the first attempt to fabricate micro 3D structures on DMF chips for precise droplet splitting to achieve one drop multiple analysis. The structures were constructed by fabricating SU8 blades of different height on the dielectric layer. The droplet splitting is more consistent and controllable compared with the current 3-electrode splitting methods. With this new method, DNA multiplex detection was successfully performed in parallel with a single fluorescence channel. All these together had confirmed its potential for a wide range of multi-step biochemical applications including post-PCR molecular detection for point-of-care disease diagnostics.

KeywordDigital Microfluidic Splitting Electrowetting Micro Structures Multiplex Detection
URLView the original
Language英语
Fulltext Access
Document TypeConference paper
CollectionDEPARTMENT OF ELECTRICAL AND COMPUTER ENGINEERING
INSTITUTE OF MICROELECTRONICS
Affiliation1.State-Key Laboratory of Analog and Mixed-Signal VLSI, University of Macau, MACAO
2.Department of ECE, Faculty of Science and Technology, University of Macau, MACAO
3.On leave from Instituto Superior Técnico, Universidade de Lisboa, PORTUGAL
First Author AffilicationUniversity of Macau;  Faculty of Science and Technology
Recommended Citation
GB/T 7714
C. Dong,Y.W. Jia,T.L. Chen,et al. Digital microfluidic chip with blade structures for precise droplet splitting[C],2016:892-893.
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