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Inorganic nanocarriers for platinum drug delivery
Ping’anMa; Haihua Xiao; Chunxia Li; Yunlu Dai; Ziyong Cheng; Zhiyao Hou; Jun Lin
2015-12
Source PublicationMaterials Today
ISSN1369-7021
Volume18Issue:10Pages:554-564
Abstract

Nowadays platinum drugs take up almost 50% of all the clinically used anticancer drugs. Besides cisplatin, novel platinum agents including sterically hindered platinum (II) drugs, chemically reductive platinum (IV) drugs, photosensitive platinum (IV) drugs, and multinuclear platinum drugs have been developed recently, with a few entering clinic trials. Rapid development of nanobiotechnology makes targeted delivery of anticancer platinum agents to the tumor site possible, while simultaneously minimizing toxicity and maximizing the drug efficacy. Being versatile drug carriers to deliver platinum drugs, inorganic nanovehicles such as gold nanoparticles, iron oxide nanomaterials, carbon nanotubes, mesoporous nanosilica, metal-organic frameworks (MOFs), have been extensively studied over the past decades. In contrast to conventional polymeric and lipid nanoparticles, inorganic nanoparticles based drug carriers are peculiar as they have shown excellent theranostic effects, revealing themselves an indispensable part of future nanomedicine. Here, we will elaborate recent research advances on fabrication of inorganic nanoparticles for platinum drug delivery.

DOIhttps://doi.org/10.1016/j.mattod.2015.05.017
Indexed BySCI
Language英语
WOS Research AreaMaterials Science
WOS SubjectMaterials Science, Multidisciplinary
WOS IDWOS:000366576000020
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Cited Times [WOS]:56   [WOS Record]     [Related Records in WOS]
Document TypeJournal article
CollectionFaculty of Health Sciences
Corresponding AuthorJun Lin
AffiliationState Key Laboratory of Rare Earth Resource Utilization, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun 130022, PR China
Recommended Citation
GB/T 7714
Ping’anMa,Haihua Xiao,Chunxia Li,et al. Inorganic nanocarriers for platinum drug delivery[J]. Materials Today,2015,18(10):554-564.
APA Ping’anMa.,Haihua Xiao.,Chunxia Li.,Yunlu Dai.,Ziyong Cheng.,...&Jun Lin.(2015).Inorganic nanocarriers for platinum drug delivery.Materials Today,18(10),554-564.
MLA Ping’anMa,et al."Inorganic nanocarriers for platinum drug delivery".Materials Today 18.10(2015):554-564.
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