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A pH-driven ring translocation switch against cancer cells
Cheng, Qian1; Yin, Hang1; Rosas, Roselyne2; Gigmes, Didier3; Ouari, Olivier3; Wang, Ruibing1; Kermagoret, Anthony3; Bardelang, David3
2018-12-21
Source PublicationCHEMICAL COMMUNICATIONS
ISSN1359-7345
Volume54Issue:98Pages:13825-13828
AbstractA molecular switch built with cucurbit[7]uril and a 3-station viologen-phenylene-imidazole compound exhibited pH actuated ring translocation with high fatigue resistance (up to 10(2) cycles). The switch movement was harnessed toward selectively masking the toxicity of the viologen fragment at neutral pH near non-cancerous cells, while exposing it at acid pH near cancer cells.
DOI10.1039/c8cc08681h
URLView the original
Indexed BySCI
Language英语
WOS Research AreaChemistry
WOS SubjectChemistry, Multidisciplinary
WOS IDWOS:000452480600010
PublisherROYAL SOC CHEMISTRY
Fulltext Access
Citation statistics
Cited Times [WOS]:2   [WOS Record]     [Related Records in WOS]
Document TypeJournal article
CollectionInstitute of Chinese Medical Sciences
Affiliation1.Univ Macau, Inst Chinese Med Sci, State Key Lab Qual Res Chinese Med, Ave Univ, Taipa, Macau, Peoples R China;
2.Aix Marseille Univ, CNRS, Spectropole, FR 1739, Marseille, France;
3.Aix Marseille Univ, CNRS, ICR, Marseille, France
First Author AffilicationUniversity of Macau
Recommended Citation
GB/T 7714
Cheng, Qian,Yin, Hang,Rosas, Roselyne,et al. A pH-driven ring translocation switch against cancer cells[J]. CHEMICAL COMMUNICATIONS,2018,54(98):13825-13828.
APA Cheng, Qian.,Yin, Hang.,Rosas, Roselyne.,Gigmes, Didier.,Ouari, Olivier.,...&Bardelang, David.(2018).A pH-driven ring translocation switch against cancer cells.CHEMICAL COMMUNICATIONS,54(98),13825-13828.
MLA Cheng, Qian,et al."A pH-driven ring translocation switch against cancer cells".CHEMICAL COMMUNICATIONS 54.98(2018):13825-13828.
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