A pH-driven ring translocation switch against cancer cells | |
Cheng, Qian1; Yin, Hang1; Rosas, Roselyne2; Gigmes, Didier3; Ouari, Olivier3; Wang, Ruibing1; Kermagoret, Anthony3; Bardelang, David3 | |
2018-12-21 | |
Source Publication | CHEMICAL COMMUNICATIONS
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ISSN | 1359-7345 |
Volume | 54Issue:98Pages:13825-13828 |
Abstract | A molecular switch built with cucurbit[7]uril and a 3-station viologen-phenylene-imidazole compound exhibited pH actuated ring translocation with high fatigue resistance (up to 10(2) cycles). The switch movement was harnessed toward selectively masking the toxicity of the viologen fragment at neutral pH near non-cancerous cells, while exposing it at acid pH near cancer cells. |
DOI | 10.1039/c8cc08681h |
URL | View the original |
Indexed By | SCI |
Language | 英语 |
WOS Research Area | Chemistry |
WOS Subject | Chemistry, Multidisciplinary |
WOS ID | WOS:000452480600010 |
Publisher | ROYAL SOC CHEMISTRY |
Fulltext Access | |
Citation statistics | |
Document Type | Journal article |
Collection | University of Macau |
Affiliation | 1.Univ Macau, Inst Chinese Med Sci, State Key Lab Qual Res Chinese Med, Ave Univ, Taipa, Macau, Peoples R China; 2.Aix Marseille Univ, CNRS, Spectropole, FR 1739, Marseille, France; 3.Aix Marseille Univ, CNRS, ICR, Marseille, France |
First Author Affilication | University of Macau |
Recommended Citation GB/T 7714 | Cheng, Qian,Yin, Hang,Rosas, Roselyne,et al. A pH-driven ring translocation switch against cancer cells[J]. CHEMICAL COMMUNICATIONS,2018,54(98):13825-13828. |
APA | Cheng, Qian.,Yin, Hang.,Rosas, Roselyne.,Gigmes, Didier.,Ouari, Olivier.,...&Bardelang, David.(2018).A pH-driven ring translocation switch against cancer cells.CHEMICAL COMMUNICATIONS,54(98),13825-13828. |
MLA | Cheng, Qian,et al."A pH-driven ring translocation switch against cancer cells".CHEMICAL COMMUNICATIONS 54.98(2018):13825-13828. |
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