Current Progresses of Exosomes as Cancer Diagnostic and Prognostic Biomarkers
Huang, Tao; Deng, Chu-Xia
AbstractCancer related exosomes are nano-size membrane vesicles that play important roles in tumor microenvironment. Emerging evidence indicates that exosomes can load unique cargoes, including proteins and nucleic acids that reflect the condition of tumor. Therefore, exosomes are being used as diagnostic and prognostic biomarkers for various cancers. In this review, we describe the current progresses of cancer related exosomes, including their biogenesis, molecular contents, biological functions, sources where they are derived from, and methods for their detection. We will also discuss the current exosomal biomarkers and the utilization of them for early diagnosis and prognostics in cancer.
Keywordexosomes cancer biomarkers therapy diagnosis prognosis
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Indexed BySCI
WOS Research AreaBiochemistry & Molecular Biology ; Life Sciences & Biomedicine - Other Topics
WOS SubjectBiochemistry & Molecular Biology ; Biology
WOS IDWOS:000453258300001
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Cited Times [WOS]:21   [WOS Record]     [Related Records in WOS]
Document TypeJournal article
CollectionUniversity of Macau
AffiliationUniv Macau, Fac Hlth Sci, Macau, Peoples R China
First Author AffilicationUniversity of Macau
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GB/T 7714
Huang, Tao,Deng, Chu-Xia. Current Progresses of Exosomes as Cancer Diagnostic and Prognostic Biomarkers[J]. INTERNATIONAL JOURNAL OF BIOLOGICAL SCIENCES,2019,15(1):1-11.
APA Huang, Tao,&Deng, Chu-Xia.(2019).Current Progresses of Exosomes as Cancer Diagnostic and Prognostic Biomarkers.INTERNATIONAL JOURNAL OF BIOLOGICAL SCIENCES,15(1),1-11.
MLA Huang, Tao,et al."Current Progresses of Exosomes as Cancer Diagnostic and Prognostic Biomarkers".INTERNATIONAL JOURNAL OF BIOLOGICAL SCIENCES 15.1(2019):1-11.
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